Cook lasagna noodles according to package instructions. Drain and rinse with cold water.
In a large pan over medium-high heat, cook ground beef until no longer pink, about 5-7 minutes. Add diced onion and cook until softened, about 3-4 minutes. Stir in minced garlic, salt, pepper, and oregano, sautéing for an additional minute. Finally, add marinara sauce and simmer for about 10 minutes before removing from heat.
Spread 1/2 cup of the meat sauce on the bottom of a casserole dish to prevent sticking.
In a mixing bowl, combine ricotta cheese, egg, parmesan cheese, 1 1/2 cups mozzarella cheese, and chopped parsley. Mix until well combined.
To assemble the roll-ups, spread a layer of the cheese mixture over each lasagna noodle, add a strip of meat sauce down the center, then roll up tightly. Place each roll seam side down in the casserole dish.
Once all roll-ups are placed in the dish, pour the remaining meat sauce over the top and sprinkle remaining mozzarella cheese evenly.
Cover the dish with foil and bake at 375°F for 40 minutes. Remove foil and broil for an additional 2-3 minutes until cheese is golden and bubbly.
Garnish with additional parsley before serving for a fresh touch.
Notes
For a vegetarian option, substitute beef with plant-based crumbles. For a spicy kick, add red pepper flakes to the meat sauce.